金长文 |
金长文
[个人简历]
北京大学生命科学学院教授, 北京大学化学与分子工程学院教授, 北京核磁共振中心首席科学家
fax : 86 - 10 - 6275-3807
tel : 86 - 10 - 6275-6004
北京市海淀区颐和园路5号，北京大学生命科学学院 , 北京 , 中国 , postcode：100871
科研领域描述
本实验室主要兴趣在于：
生物大分子结构与功能关系的研究
生物大分子动力学的核磁共振研究
核磁共振方法学的研究
代表性论文
Hongwei Li, Fan Yang, Xue Kang, Bin Xia and Changwen Jin*. , Solution Structures and Backbone Dynamics of Escherichia coli Rhodanese PspE in Its Sulfur-Free and Persulfide-Internediate forms: Implications for the Catalytic Mechanism of Rhodanese , Biochemistry , 2008 , (in press)
Caifang Yu, You Li, Bin Xia, and Changwen Jin*. , Solution structure of the cryptic mannitol-specific phosphotransferase enzyme IIA CmtB from Escherichia coli. , Biochem. Biophys. Res. Commun. , 2007 , 362(4), 1001-1006,
You Li, Yunfei Hu, Wenyu Fu, Bin Xia, and Changwen Jin*. , Solution structure of the bacterial chemotaxis adaptor protein CheW from Escherichia coli. , Biochem. Biophys. Res. Commun. , 2007 , 360(4), 863-867
Lei Wang, Bin Xia, and Changwen Jin*. , Solution structure of Escherichia coli HypC , Biochem. Biophys. Res. Commun. , 2007 , 361(3), 665-669
Fan Yang, Wei Hu, Huimin Xu, Congmin Li, Bin Xia, and Changwen Jin*. , Solution structure and backbone dynamics of an endopeptidase HycI from Escherichia coli: implications for mechanism of the [NiFe] hydrogenase maturation , J. Biol. Chem. , , 2007 , 282(6), 3856-3863
Wenyu Fu, Fan Yang, Xue Kang, Xinxin Zhang, You Li, Bin Xia, and Changwen Jin*. , First structure of the polymyxin resistance proteins , Biochem. Biophys. Res. Commun. , 2007 , 361(4), 1033-1037
You Li1, Yunfei Hu1, Xinxin Zhang, Huimin Xu, Ewen Lescop, Bin Xia, and Changwen Jin*. , Conformational fluctuations coupled to the thiol-disulfide transfer between thioredoxin and arsenate reductase in Bacillus subtilis , J. Biol. Chem. , 2007 , 282(15), 11078-11083 , ( 1 equal contributions )
Xinxin Zhang, Yunfei Hu, Xianrong Guo, Ewen Lescop, You Li, Bin Xia, and Changwen Jin* , The Bacillus subtilis YKUV is a thiol-disulfide oxidoreductase revealed by its redox structures and activity , J. Biol. Chem. , , 2006 , 281(12), 8296-8304
Xianrong Guo1, You Li1, Kuan Peng, Yunfei Hu, Congmin Li, Bin Xia, and Changwen Jin*. , Solution structures and backbone dynamics of arsenate reductase from Bacillus subtilis: reversible conformational switch associated with arsenate reduction , J. Biol. Chem., , 2006 , 280(47), 39601-39608 , ( 1 equal contributions )
Yunfei Hu, You Li, Xinxin Zhang, Xianrong Guo, Bin Xia, and Changwen Jin*. , Solution structures and backbone dynamics of a flavodoxin MioC from Escherichia coli in both apo- and holo-forms: implications for cofactor binding and electron transfer , J. Biol. Chem. , , 2006 , 281(46), 35454-35466
Huimin Xu, Bin Xia, and Changwen Jin*. , Solution Structure of a Low-Molecular-Weight Protein Tyrosine Phosphatase from Bacillus subtilis , J. Bacteriol. , 2006 , 188(4), 1509-1517
Ewen Lescop, Yunfei Hu, Huimin Xu, Wei Hu, Juan Chen, Bin Xia, and Changwen Jin*. , The solution structure of Escherichia coli Wzb reveals a novel substrate recognition mechanism of prokaryotic low molecular weight protein tyrosin phophatases , J. Biol. Chem., , 2006 , 281(28), 19570-19577
Xue Kang, Yunfei Hu, You Li, Xianrong Guo, Xiaolu Jiang, Luhua Lai, Bin Xia, and Changwen Jin*. , Structural, biochemical and dynamic characterizations of the hRPB8 subunit of human RNA polymerases , J. Biol. Chem., , 2006 , 281(26), 18216-18226
Huimin Xu, Peng Zhang, and Changwen Jin*. , Letter to the Editor. NMR assignments of a low molecular weight protein tyrosine phosphatase (PTPase) from Bacillus subtilis , J. Biomol. NMR , 2005 , 31, 363
Congmin Li, Xianrong Guo, Zhongchao Jia, Bin Xia, and Changwen Jin*. , Solution Structure of an Antifreeze Protein CfAFP-501 from Choristoneura fumiferana , J. Biomol. NMR , 2005 , 32, 251-256
Xinxin Zhang, Caifang Yu, Bin Xia, and Changwen Jin*. , NMR assignment of new thioredoxin-like protein YkuV from Bacillus subtilis , J. Biomol. NMR , 2005 , 32, 258,
Congmin Li, and Changwen Jin*. , Letter to the Editor: 1H, 13C and 15N resonance assignments of the antifreeze protein cfAFP-501 from spruce budworm at different temperatures , J. Biomol. NMR , 2004 , 30, 101-102
Kuan Peng, Xiaodong Su, Bin Xia, and Changwen Jin*. , Letter to the Editor: 1H, 13C and 15N resonance assignments of a Bacillus Subtilis arsenate reductase , J. Biomol. NMR , 2004 , 29，459－460 |
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